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CBD Studies Database - CBD + Opioid Use/Withdrawal

Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study
Summary: This study aims to investigate the impact of full hemp extract cannabidiol (CBD) on opioid use and quality of life indicators among chronic pain patients.
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CBD for Pain: Is Cannabidiol a Natural Alternative to Opioid Drugs? Summary: This study investigates CBD as a safe and natural alternative to opioids.
Read the full study here.  
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Cannabidiol: Swinging the Marijuana Pendulum From ‘Weed’ to Medication to Treat the Opioid Epidemic
Summary: This study addresses the rapidly changing sociopolitical marijuana landscape and provides a foundation for the therapeutic development of medicinal cannabidiol to address the current opioid abuse crisis.
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Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis
Summary: This study’s aim was to conduct a systematic review to determine the opioid-sparing potential of cannabinoids.
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Safety and pharmacokinetics of oral cannabidiol when administered concomitantly with intravenous fentanyl in humans
Summary: This study determines CBD safety and pharmacokinetics when administered concomitantly with a high-potency opioid in healthy subjects.
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Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report
Summary: This study tests tolerance to cannabis and cannabis withdrawal symptoms and describes the case of a 19‐year‐old woman with cannabis withdrawal syndrome treated with cannabidiol (CBD) for 10 days.
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Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage 
Summary: This paper provides an overview of preclinical animal and human clinical investigations, and presents preliminary clinical data that collectively sets a strong foundation in support of the further exploration of CBD as a therapeutic intervention against opioid relapse. 
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