All locations will be closing at 4 p.m due to the weather.

CBD Studies Database - CBD + Epilepsy

The protocol for the Cannabidiol in children with refractory epileptic encephalopathy (CARE-E) study: a phase 1 dosage escalation study
Summary: This study’s purpose is to determine whether CBD-enriched Cannabis extract is safe and well-tolerated for pediatric patients with refractory epilepsy and to monitor the effects of CBD-enriched Cannabis extract on the frequency and duration of seizure types and on quality of life.
Read the full study here.

Cannabidiol in the Treatment of Epilepsy: A Focused Review of Evidence and Gaps 
Summary: This study researches CBD as a new therapeutic option to potentially fulfill the treatment gap in anti-seizure medications in epilepsy patients.
Read the full study here.

Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials
Summary: This study evaluates the use of CBD, in addition to common anti-epileptic drugs, in the severe treatment-resistant epilepsy through an overview of recent literature and clinical trials aimed to study the effects of the CBD treatment in different forms of epilepsy. 
Read the full study here.

Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?
Summary: This study’s purpose is to clarify the relative contribution of CBD to improved seizure outcomes in the trial data for the subgroup of patients not comedicated with clobazam.
Read the full study here.

Cannabidiol in the Treatment of Epilepsy
Summary: This study’s aim is to thoroughly review available research data and practical recommendations to provide the treating physician with the necessary information for counseling patients with epilepsy.
Read the full study here.

An Open Retrospective Study of a Standardized Cannabidiol Based-Oil in Treatment-Resistant Epilepsy
Summary: This study evaluates the effectiveness of add-on therapy with a standardized CBD-based oil in treatment-resistant epilepsy (TRE) patients.
Read the full study here.

A preliminary study of the effects of cannabidiol (CBD) on brain structure in patients with epilepsy
Summary: This preliminary study examines whether daily CBD dose of 15–25 mg/kg produces cerebral macrostructure changes and, if present, how they relate to changes in seizure frequency.
Read the full study here.

Long‐term safety and treatment effects of cannabidiol in children and adults with treatment‐resistant epilepsies: Expanded access program results
Summary: This study reports interim results on the safety and efficacy of CBD in patients with treatment-resistant epilepsies in expanded access programs.
Read the full study here.

A dose ranging safety and pharmacokinetic study of cannabidiol (CBD) in children with Dravet syndrome (GWPCARE1)
Summary: This controlled study evaluated dose-ranging safety, tolerability, and pharmacokinetics of supplemental CBD in children ages 4-10 with Dravet syndrome and then determined the dosage that assessed the safety and efficacy in a larger population.
Read the full study here.

Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents – An observational, longitudinal study
Summary: This observational study evaluates the efficacy of CBD-enriched medical cannabis for the treatment of refractory epilepsy. According to parental reports, results suggest that adding CBD-enriched cannabis extract to the treatment regimen of patients with refractory epilepsy may result in a significant reduction in seizure frequency.
Read the full study here.

Drug–drug interaction between clobazam and cannabidiol in children with refractory epilepsy
Summary: This study evaluates cannabidiol as a possible adjuvant treatment of refractory epilepsy in children testing drug-drug interactions with clobazam.
Read the full study here.
.
.